| 货号 | 1487/1 |
| 别名 | AYPGKF-NH2 |
| 供应商 | Tocris |
| 生物活性 | Selective PAR4 receptor agonist peptide. Stimulates platelet aggregation in vitro(EC50 = 15 μM). Exhibits an increase in paw thickness in the paw edema inflammation model in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 680.8 |
| 分子式 | C34H48N8O7 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| CAS号 | 352017-71-1 |
| 序列号 | AYPGKF (Modifications: Phe-6 = C-terminal amide) |
| 参考文献 | Hollenburget al (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br.J.Pharmacol. 143 443. PMID: 15451771. Hollenberg and Saifeddine (2001) Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides. Can.J.Physiol.Pharmacol. 79 439. PMID: 11405248. Faruqiet al (2000) Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. J.Biol.Chem. 275 19728. PMID: 10779527. |