| 货号 | 1642/1 |
| 供应商 | Tocris |
| 生物活性 | Potent endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Displays arterio-selective vasoconstriction and vasodilatation in mammals in vitroandin vivo, effects which vary between species. Also has been shown to mediate bronchoconstriction. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1388.57 |
| 分子式 | C64H85N13O18S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 251293-28-4 |
| 序列号 | ETPDCFWKYCV (Modifications: Disulfide bridge between 5 - 10) |
| 参考文献 | Maguire and Davenport (2002) Is urotensin-II the new endothelin? Br.J.Pharmacol 137 579. PMID: 12381671. Nothackeret al (1999) Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat.Cell.Biol. 1 383. PMID: 10559967. Coulouarnet al (1998) Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurones of the spinal cord. Proc.Natl.Acad.Sci.U.S.A. 95 15803. PMID: 9861051. |