PF 5081090 (10 MG)
货号：
4362/10 基本售价：
3945.9 元 规格：
10 mg
产品信息
概述| 货号 | 4362/10 |
| 别名 | (αR)-4-(2-Fluoro-4-methoxyphenyl)-N-hydroxy-α-methyl-α-(methylsulfonyl)-2-oxo-1(2H)-pyridinebutanamide |
性能| 供应商 | Tocris |
| 生物活性 | Potent antibacterial agent which disrupts lipid bilayer synthesis through inhibition of LpxC (IC50 = 1.1 nM in Pseudomonas aeruginosa); effective against a range of gram negative bacteria. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 412.43 |
| 分子式 | C18H21FN2O6< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Montgomeryet al (2012) Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections. J.Med.Chem. 55 (4) 1662. PMID: 22257165. |
