| 货号 | 3337/100U |
| 供应商 | Tocris |
| 生物活性 | Cocaine- and amphetamine-regulated transcript (CART) with potent appetite-suppressing activity. Satiety factor; inhibits normal and starvation-induced feeding. Closely related to the actions of leptin and neuropeptide Y; blocks the neuropeptide Y-induced feeding response. Induces anxiety and stress behavior in rodents. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 5259.21 |
| 分子式 | C226H367N65O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | IPIYEKKYGQVPMCDAGEQCAVRKGARIGK (Modifications: Disulfide bridge between 14 - 32, 20 - 40, 34 - 47) |
| 参考文献 | Chakiet al (2003) Cocaine- and amphetamine-regulated transcript peptide produces anxiety-like behavior in rodents. Eur.J.Pharmacol. 464 49. PMID: 12600694. Ludvigsenet al (2001) Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold. Biochemistry 40 9082. PMID: 11478874. Thimet al (1998) CART, a new anorectic peptide. Int.J.Biochem.Cell Biol. 30 1281. PMID: 9924797. |