ACHP (10 MG)
货号：
4547/10 基本售价：
3945.9 元 规格：
10 mg
产品信息
概述| 货号 | 4547/10 |
| 别名 | 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile |
性能| 供应商 | Tocris |
| 生物活性 | IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively). Selective for IKKα and IKKβ over IKK3, Syk and MAPKKK4 (IC50 values are > 20 μM). Inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 364.44 |
| 分子式 | C21H24N4O2 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Sandaet al (2005) Growth inhibition of multiple myeloma cells by a novel IκB kinase inhibitor. Clin.Cancer Res. 11 1974. PMID: 15756023. |
