| 货号 | 2411/1 |
| 别名 | N-[(1,1-Dimethylethoxy)carbonyl]-L- |
| 供应商 | Tocris |
| 生物活性 | Potent CCK1 agonist (IC50 = 3.7 nM) with 1200-fold selectivity over the CCK2 receptor. Suppresses food intake following central or peripheral administration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 840.97 |
| 分子式 | C44H56N8O9 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20mM PBS buffer |
| CAS号 | 130408-77-4 |
| 序列号 | XWKDF (Modifications: Trp-1 = Boc-Trp, Lys-3 = Lys(Tac), Phe-5 = N-methyl-Phe & C-terminal amide) |
| 参考文献 | Asinet al (1992) A-71623, a selective CCK-A receptor agonist, suppresses food intake in the mouse, dog, and monkey. Pharmacol.Biochem.Behav. 42 699. PMID: 1513850. DeNinnoet al (1990) Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists. J.Med.Chem. 332951. Linet al (1990) Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors. Mol.Pharmacol. 39346. |