货号 | 0805/10 |
别名 | (S)-3,5-Dihydroxyphenylglycine |
供应商 | Tocris |
生物活性 | Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™. (RS)-3,5-DHPG (Cat. No. 0342) also available. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 183.16 |
分子式 | C8H9NO4 |
可溶性/溶解性 | Soluble to 50 mM in water |
CAS号 | 162870-29-3 |
参考文献 | Wisniewski and Car (2002) (S)-3,5-DHPG: a review. CNS Drug Rev. 8 101. PMID: 12070529. Sekiyamaet al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493. PMID: 8730745. Bakeret al (1995) Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist. Bioorg.Med.Chem.Lett. 5223. Schoeppet al (1994) 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J.Neurochem. 63 769. PMID: 8035201. |