| 货号 | 3054/1 |
| 供应商 | Tocris |
| 生物活性 | Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 3342.24 |
| 分子式 | C148H239ClN44O42 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 102805-45-8 |
| 序列号 | HSDAVFTDNYTRLRKQLAVKKYLNSILN (Modifications: Phe-6 = p-Cl-D-Phe, Asn-34 = C-terminal amide) |
| 参考文献 | Xieet al (2007) Vasoactive intestinal peptide transactivates the androgen receptor through a protein kinase A-dependent extracellular signal-regulated kinase pathway in prostate cancer LNCaP cells. Mol.Pharmacol. 72 73. PMID: 17430995. Pozoet al (1997) Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur.J.Pharmacol. 321 379. PMID: 9085051. Pandolet al (1986) Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6,Leu17]VIP. Am.J.Physiol. 250 G553. PMID: 2421587. |