| 货号 | 2268/10 |
| 别名 | (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2 |
| 供应商 | Tocris |
| 生物活性 | Highly selective T-type calcium channel blocker. Displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 564.57 |
| 分子式 | C30H38FN3O2.2HCl |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 357400-13-6 |
| 参考文献 | Chenet al (2010) CaV3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. J.Neurosci. 30 10360. PMID: 20685979. Huanget al (2004) NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A new selective inhibitor of T-type calcium channels. J.Pharmacol.Exp.Ther. 309 193. PMID: 14718587. |