| 货号 | 1789/1 |
| 别名 | Gastrin-releasing peptide (human) |
| 供应商 | Tocris |
| 生物活性 | Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice in vivo. Also involved in mitogenesis, and GI tract and appetite regulation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2859.4 |
| 分子式 | C130H204N38O31S2 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 93755-85-2 |
| 序列号 | VPLPAGGGTVLTKMYPRGNHWAVGHLM (Modifications: Met-27 = C-terminal amide) |
| 参考文献 | Dudai (2003) Neurobiology: Fear thou not. Nature 421 325. PMID: 12540884. Shumyatskyet al (2002) Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell 111 905. PMID: 12526815. Woodruffet al (1996) Bombesin receptors in the brain. Ann.N.Y.Acad.Sci. 780 223. PMID: 8602736. Benyaet al (1995) Expression and characterization of cloned human bombesin receptors. Mol.Pharmacol. 47 10. PMID: 7838118. |