货号 | 1983/1 |
别名 | PDGFR740Y-P |
供应商 | Tocris |
生物活性 | Cell-permeable phosphopeptide activator of PI 3-kinase. Binds with high affinity to p85 subunit of the enzyme. Displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 3270.72 |
分子式 | C141H222N43O39PS3 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | RQIKIWFQNRRMKWKKSDGGYMDMS (Modifications: Tyr-21 = pTyr) |
参考文献 | Williams and Doherty (1999) Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway. Mol.Cell.Neurosci. 13 272. PMID: 10328886. Derossiet al (1998) Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide. Biochem.Biophys.Res.Comm. 251148. |