| 货号 | 2434/10 |
| 别名 | (6aR,10aR)-3-(1,1-Dimethylheptyl)-6 |
| 供应商 | Tocris |
| 生物活性 | Highly selective CB2 receptor agonist (Ki values are 11.8 and 4888 nM for CB2 and CB1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB2 receptors expressed in CHO cells (EC50 = 3.1 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 384.6 |
| 分子式 | C26H40O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Huffman (2005) CB2 receptor ligands. Mini Rev.Med.Chem. 5 641. PMID: 16026310. Huffman (2000) The search for selective ligands for the CB2 receptor. Curr.Pharmaceut.Des. 61323. Rosset al (1999) Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630. Br.J.Pharmacol. 126 665. PMID: 10188977. |