TC-S 7005 (10 MG)
货号：
4459/10 基本售价：
3797.2 元 规格：
10 mg
产品信息
概述| 货号 | 4459/10 |
| 别名 | 3-(1,3-Benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-isoxazolo[5,4-c]pyridin-5-amine |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 359.38 |
| 分子式 | C21H17N3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Hananet al (2008) Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg.Med.Chem.Lett. 18 5186. PMID: 18790636. |
