| 货号 | 1468/1 |
| 供应商 | Tocris |
| 生物活性 | Agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2(EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo. Control peptide LRGILS-NH2 (Cat. No. 3394) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 656.82 |
| 分子式 | C29H56N10O7 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 171436-38-7 |
| 序列号 | SLIGRL (Modifications: Leu-6 = C-terminal amide) |
| 参考文献 | Kawabataet al (2001) In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse. Br.J.Pharmacol. 133 1213. PMID: 11498505. Al-Aniet al (1995) Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can.J.Physiol.Pharmacol. 73 1203. PMID: 8564891. Nystedtet al (1994) Molecular cloning of a potential proteinase activated receptor. Proc.Natl.Acad.Sci.U.S.A. 91 9208. PMID: 7937743. |