货号 | 1950/1 |
供应商 | Tocris |
生物活性 | Peptide, corresponding to residues 63 - 75 of connexin 43, which is a gap junction blocker. Attenuates rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 mM). Also inhibits IP3-induced ATP release, without inhibiting gap junctional coupling in endothelial cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1550.79 |
分子式 | C70H107N19O19S |
可溶性/溶解性 | Soluble to 2 mg/ml in water |
CAS号 | 197250-15-0 |
序列号 | VCYDKSFPISHVR |
参考文献 | Braetet al (2003) Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26. Cell Calcium 33 37. PMID: 12526886. Chaytoret al (1997) Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteries. J.Physiol. 503 99. PMID: 9288678. |