| 货号 | 2454/1 |
| 供应商 | Tocris |
| 生物活性 | Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1(IC50 values are 30.9 nM, 345 nM, >1μM, >10μM and >10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin release in the rat nucleus accumbens. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1485.8 |
| 分子式 | C74H96N14O15 |
| 可溶性/溶解性 | Soluble to 0.30 mg/ml in water |
| 序列号 | CKFFWXTFTSC (Modifications: Cyclic Cys1-Cys11, X=4-[[(1-methylethyl)amino]met |
| 参考文献 | Vasilakiet al (2004) The somatostatin receptor (sst1) modulates the release of somatostatin in the nucleus accumbens of the rat. Neuropharmacology 47 612. PMID: 15380378. Rivieret al (2001) Potent somatostatin undecapeptide agonists selective for somatostatin receptor 1 (sst1). J.Med.Chem. 44 2238. PMID: 11405660. Chenet al (1999) Structural basis for the binding specificity of a SSTR1-selective analog of somatostatin. Biochem.Biophys.Res.Commun. 258 689. PMID: 10329447. |