| 货号 | 2281/10 |
| 别名 | 2-Chloro-N-cyclopentyl-2'-methyladen |
| 供应商 | Tocris |
| 生物活性 | Potent and highly selective agonist at A1 adenosine receptors (Ki values are 3.3, 9580, 37600 and 1150 nM for human recombinant A1, A2A, A2B and A3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC50 value of 13.1 nM. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 383.83 |
| 分子式 | C16H22ClN5O4 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO |
| CAS号 | 205171-12-6 |
| 参考文献 | Cappellacciet al (2005) Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists. J.Med.Chem. 48 1550. PMID: 15743197. Franchettiet al (1998) 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. J.Med.Chem. 41 1708. PMID: 9572897. |