货号 | 4488/10 |
别名 | 3-β-D-Ribofuranosyl-3H-imidazo[4,5-b |
供应商 | Tocris |
生物活性 | Inhibitor of adenosine deaminase (Ki = 0.66 μM). Demonstrates antitumor activity in a range of leukemia cell lines. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 266.25 |
分子式 | C11H14N4O4 |
可溶性/溶解性 | Soluble to 25 mM in DMSO |
参考文献 | Cristalliet al (1993) Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res. 28253. Cristalliet al (1987) Improved synthesis and antitumor activity of 1-deazaadenosine. J.Med.Chem. 30 1686. PMID: 3625714. |