货号 | 1418/100 |
别名 | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl] |
供应商 | Tocris |
生物活性 | A phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC50 = 23 μM) and displays mixed agonist/antagonist actions at ERα and ERβ estrogen receptors. Converted into the anticancer agent piceatannol (Cat. No. 1554) by cytochrome P450 1B1. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 228.25 |
分子式 | C14H12O3 |
可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
CAS号 | 501-36-0 |
参考文献 | Baptistaet al (2013) Regulation of histone H2A.Z exprsesion is mediated by sirtuin 1 in prostate cancer. Oncotarget 4 1673. PMID: 24127549. Baur and Sinclair (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat.Rev.Drug Discov. 5 493. PMID: 16732220. Bowerset al (2000) Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β. Endocrinology 141 3657. PMID: 11014220. Fremont (2000) Biological effects of resveratrol. Life Sci. 66 663. PMID: 10680575. Chunet al (1999) Resveratrol is a selective human cytochrome P450 1A1 inhibitor. Biochem.Biophys.Res.Commun. 262 20. PMID: 10448061. Kimuraet al (1985) Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim.Biophys.Acta 834 275. PMID: 3922423. |