| 货号 | 3932/1 |
| 别名 | Nociceptin (1-11) |
| 供应商 | Tocris |
| 生物活性 | Peptide fragment containing amino acids 1-11 of Nociceptin (Cat. No. 0910). Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ,δ,κ1andκ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1098.2 |
| 分子式 | C49H75N15O14 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 20% acetonitrile / water |
| CAS号 | 178249-41-7 |
| 序列号 | FGGFTGARKSA |
| 参考文献 | Rossiet al (1998) Orphanin FQ/nociceptin analgesia in the rat. Brain Res. 792 327. PMID: 9593974. Rossiet al (1997) Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J.Pharmacol.Exp.Ther. 282 858. PMID: 9262352. Reinscheidet al (1996) Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J.Biol.Chem. 271 14163. PMID: 8662940. |