| 货号 | 3798/50 |
| 别名 | 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol |
| 供应商 | Tocris |
| 生物活性 | Selective non-peptide angiotensin AT1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA2 = 8.27). Orally active antihypertensive agent. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 461 |
| 分子式 | C22H22CIKN6O |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 124750-99-8 |
| 参考文献 | Rhalebet al (1991) DuP 753 is a specific antagonist for the angiotensin receptor. Hypertension 17 480. PMID: 1672862. Wonget al (1990) Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2). J.Pharmacol.Exp.Ther. 255 584. PMID: 2243344. Wonget al (1990) Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP an orally active antihypertensive agent. J.Pharmacol.Exp.Ther. 252 719. PMID: 2179531. |