| 货号 | 3396/1 |
| 供应商 | Tocris |
| 生物活性 | Synthetic vasopressin analog that acts as an agonist at V1B and V2 receptors (EC50 values are 11.4 and 23.9 nM and Ki values are 5.84 and 65.9 nM respectively). Prevents polycystic kidney disease formation and exhibits antidiuretic, antiproliferative, hemostatic and hypotensive activity in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1069.22 |
| 分子式 | C46H6N14O12S2 |
| 可溶性/溶解性 | Soluble to 4 mg/ml in water |
| CAS号 | 16679-58-6 |
| 序列号 | XYFQNCPRG (Modifications: X = Mpr, Arg-8 = D-Arg, Gly-9 = C-terminal amide, Cyclized = X-1 - Cys-6) |
| 参考文献 | Torres (2008) Vasopressin antagonists in polycystic kidney disease. Semin.Nephrol. 28 306. PMID: 18519091. Gomezet al (2006) Desmopressin and other synthetic vasopressin analogues in cancer treatment. Bull.Cancer 93 E7. PMID: 16517412. Saitoet al (1997) 1-Desamino-8-D-arginine vasopressin (DDAVP) as an agonist on V1b vasopressin receptor. Biochem.Pharmacol. 53 1711. PMID: 9264324. |