| 货号 | 1883/1 |
| 别名 | [Ala32]H2B(29-35) |
| 供应商 | Tocris |
| 生物活性 | Competitive inhibitor of cGMP-dependent protein kinase (PKG); analog of a substrate peptide corresponding to a phosphorylation site of histone H2B. Competes with synthetic substrates (Ki = 86 mM) but does not inhibit phosphorylation of intact histones by PKG. Inhibits phosphorylation of intact histones by PKA. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 943.12 |
| 分子式 | C38H74N18O10 |
| CAS号 | 82801-73-8 |
| 序列号 | RKRARKE |
| 参考文献 | Bhatnagaret al (1988) Synthetic peptide analogues differentially alter the binding affinities of cyclic nucleotide dependent protein kinases for nucleotide substrates. Biochemistry 27 1988. PMID: 2837278. Glasset al (1986) Differential and common recognition of the catalytic sites of the cGMP-dependent and cAMP-dependent protein kinases by inhibitory peptides derived from the heat-stable inhibitor protein. J.Biol.Chem. 261 12166. PMID: 3017964. Glass (1983) Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein kinases to synthetic peptide inhibitors. Biochem.J. 213 159. PMID: 6615418. |