| 货号 | 3422/1 |
| 供应商 | Tocris |
| 生物活性 | Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro(IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1610.9 |
| 分子式 | C75H114N22O18 |
| 可溶性/溶解性 | Soluble to 10 mg/ml in water |
| CAS号 | 108437-88-3 |
| 序列号 | XQRLGNQWAVGFLL (Modifications: X = Glp, Phe-12 = D-Phe, Leu-14 = C-terminal amide) |
| 参考文献 | Flynn (1997) Bombesin receptor antagonists block the effects of exogenous bombesin but not of nutrients on food intake. Physiol.Behav. 62 791. PMID: 9284499. Meraliet al (1988) (d-Phe12) bombesin and substance P analogues function as central bombesin receptor antagonists. Synapse 2 282. PMID: 2463692. Heinz-Erianet al (1987) [d-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. Am.J.Physiol. 252 G439. PMID: 2435173. |