货号 | 1913/1 |
供应商 | Tocris |
生物活性 | Bombesin receptor antagonist; inhibits bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Centrally active in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1629.9 |
分子式 | C74H112N22O18S |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
CAS号 | 108437-87-2 |
序列号 | XQRLGNQWAVGFLM (Modifications: X = Glp, Phe-12 = D-Phe, Gly-14 = C-terminal amide) |
参考文献 | Meraliet al (1988) (D-Phe12) Bombesin and substance P analogues function as central bombesin receptor antagonists. Synapse 2 282. PMID: 2463692. Moodyet al (1988) Localization of receptors for bombesin-like peptides in the rat brain. Ann.N.Y.Acad.Sci. 547 114. PMID: 2853589. Heinz-Erianet al (1987) [D-Phe12]Bombesin analogues: a new class of bombesin receptor antagonists. Am.J.Physiol. 252 G439. PMID: 2435173. |