AdPLA2 Blocking Peptide
货号:
10338-1ea 基本售价:
1498.0 元 规格:
200 ug
产品信息
概述货号 | 10338-1ea |
描述 | The PLA2 superfamily consists of multiple enzymes that catalyze the hydrolysis of fatty acids from the sn-2 position in phospholipids. AdPLA2 is the first member of Group XVI phospholipases (PLA). This pH- and calcium-dependent phospholipase is highly expressed in adipose tissue and is associated with adipocyte differentiation and lipolysis. It has been implicated as a major player in the development of obesity.1,2 Human AdPLA2 is a 162 amino acid protein with a calculated molecular weight of 18 kDa. It contains a transmembrane region and shares 70-75% sequence similarity with the mouse and rat proteins, respectively. Cayman’s antibody was raised against the C-terminal region of the human protein. |
别名 | Adipose Phospholipase A2;HRasLS3;HRas-like supressor 3; |
性能供应商 | Cayman |
应用文献 |
1.Jaworski, K.,Ahmadian, M.,Duncan, R.E., et al. AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Nature Medicine 15(2), 159-168 (2009). 2.Duncan, R.E.,Sarkadi-Nagy, E.,Jaworski, K., et al. Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA). The Journal of Biological Chemisty 283(37), 25428-25436 (2008).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
稳定性 | ≥ 2 years |
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