| 货号 | 1927/1 |
| 别名 | N-Acetyl-O-phosphono-L-tyrosyl-L-α-g |
| 供应商 | Tocris |
| 生物活性 | Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 803.71 |
| 分子式 | C32H46N5O17P |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 159439-02-8 |
| 序列号 | YEEIE (Modifications: Tyr-1 = pTyr with C-terminal Ac) |
| 参考文献 | Parket al (2002) Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains. Bioorg.Med.Chem.Lett. 12 2711. PMID: 12217360. Pacofskyet al (1998) Potent dipeptide inhibitors of the pp60c-src SH2 domain. J.Med.Chem. 41 1894. PMID: 9599239. Gilmeret al (1994) Peptide inhibitors of src SH3-SH2-phosphoprotein interactions. J.Biol.Chem. 269 31711. PMID: 7527393. |