AZD-7762
货号:
9414-5 基本售价:
1458.0 元 规格:
5mg
产品信息
概述货号 | 9414-5 |
描述 | AZD7762 is a potent, ATP-competitive, reversible, checkpoint kinase inhibitor with IC₅₀s at 5 nM and <10 nM for Chk1 and Chk2, respectively. AZD 7762 abrogates DNA damage-induced S and G2 checkpoints with an EC₅₀ value of 10 nM and potentiates the efficacy of DNA-damage repair prohibitive agents, gemcitabine and topotecan, both in vitro and in various tumor xenografts by modulating downstream checkpoint pathway proteins. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
CAS号 | 860352-01-8 |
外观 | White solid |