货号 | 2262/1 |
别名 | WRW4 |
供应商 | Tocris |
生物活性 | Selective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β42 peptide. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1104.28 |
分子式 | C61H65N15O6 |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | WRWWWW (Modifications: Trp-6 = C-terminal amide) |
参考文献 | Baeet al (2004) Identification of peptides that antagonize formyl peptide receptor-like 1-mediating signaling. J.Immunol. 173 607. PMID: 15210823. |