货号 | 0582/50 |
别名 | 1-[10,11-Dihydro-8-(methylthio)dibe |
供应商 | Tocris |
生物活性 | Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 472.62 |
分子式 | C20H24N2S2.C4H4O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 20229-30-5 |
参考文献 | Wilkinson and Middlemiss (1992) Metitepine distinguishes two receptors mediating inhibition of [3H]-5-hydroxytryptamine release in guinea pig hippocampus. Naunyn Schmiedebergs Arch.Pharmacol. 345 696. PMID: 1321958. Hoyer (1989) The peripheral actions of 5-HT. Ed. Fozard. Oxford.. |