| 货号 | 4084/1 |
| 供应商 | Tocris |
| 生物活性 | Neuroprotective peptide that binds to amyloid beta (Aβ). Protects neurons against toxic effects of Aβ(1-42)in vitroandin vivo. Potential therapeutic in the treatment of Alzheimer's Disease. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 652.75 |
| 分子式 | C33H44N6O8 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 10% acetonitrile / water |
| 序列号 | LPYFD-NH2 (Modifications: Asp-5 = C-terminal amide) |
| 参考文献 | Juhaszet al (2009) An intraperitoneally administered pentapeptide protects against Aβ (1-42) induced neuronal excitation in vivo. J.Alzheimer's Dis. 16189. Szegediet al (2005) Pentapeptides derived from Aβ1-42 protect neurons from the modulatory effects of Aβ fibrils- an in vitro and in vivo electrophysiological study. Neurobiology of Disease 18 499. PMID: 15755677. |