| 货号 | 1520/1 |
| 别名 | 1,3,4,6,8,13-Hexahydroxy-10,11-dime |
| 供应商 | Tocris |
| 生物活性 | Photosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC50 = 7.5 μM) and is preferentially cytotoxic to tumor cells upon stimulation by visible light. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 504.45 |
| 分子式 | C30H16O8 |
| 可溶性/溶解性 | Soluble to 10 mM in ethanol with gentle warming and to 50 mM in DMSO |
| CAS号 | 548-04-9 |
| 参考文献 | Agostiniset al (2002) Hypericin in cancer treatment: more light on the way. Int.J.Biochem.Cell Biol. 34 221. PMID: 11849990. Hwanget al (2001) Inhibition of c-erbB-2 expression and activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 21 2649. PMID: 11724334. Lenardet al (1993) Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal: inhibition of fusion and syncytia formation. Proc.Natl.Acad.Sci.U.S.A. 90 158. PMID: 7678335. |