货号 | 1964/50 |
别名 | 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethy |
供应商 | Tocris |
生物活性 | Lipophilic agent derived from cottonseed. Exhibits multiple biological effects including antifertility and anticancer activity. Proapoptotic; downregulates Bcl-2 and Bcl-XL. R-enantiomer available (Cat. No. 3367). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 518.56 |
分子式 | C30H30O8 |
可溶性/溶解性 | Soluble to 25 mM in ethanol with gentle warming and to 25 mM in DMSO |
CAS号 | 303-45-7 |
参考文献 | Zhanget al (2003) Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochem.Pharmacol. 66 93. PMID: 12818369. Coutinh (2002) Gossypol: a contraceptive for men. Contraception 65 259. PMID: 12020773. Vander Jagtet al (2000) Gosspyol: prototype of inhibitors targeted to dinucleotide folds. Curr.Med.Chem. 7 479. PMID: 10702620. |