| 货号 | 2964/50 |
| 别名 | 4-Amino-2-[4-(1,4-benzodioxan-2-car |
| 供应商 | Tocris |
| 生物活性 | Selectiveα1-adrenoceptor antagonist (pKi values are 9.0, 8.5 and 8.4 for human α1B,α1Aandα1D receptors respectively). Displays antihypertensive activity. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 547.58 |
| 分子式 | C23H25N5O5.CH3SO3H |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO |
| CAS号 | 77883-43-3 |
| 参考文献 | Maet al (2006) Chiral selective effects of doxazosin enantiomers on blood pressure and urinaruy bladder pressure in anesthetized rats. Acta Pharmacol.Sinica 271423. Kennyet al (1996) Evaluation of the pharmacological selectivity profile of α1 adrenoceptor antagonists at prostatic α1 adrenoceptors: binding functional and in vivo studies. Br.J.Pharmacol. 118 871. PMID: 8799556. Alabaster and Davey (1986) The α1-adrenoceptor antagonist profile of doxazosin: preclinical pharmacology. Br.J.Clin.Pharmacol. 21 9S. PMID: 2871857. |