| 货号 | 0685/1G |
| 别名 | (2S-cis)-3-(Acetyloxy)-5-[2-(dimeth |
| 供应商 | Tocris |
| 生物活性 | Antihypertensive and cardioprotective agent; an inhibitor of L-type Ca2+channels. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 450.98 |
| 分子式 | C22H26N2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Krauset al (1998) Molecular mechanisms of diltiazem interaction with L-type Ca2+ channels. J.Biol.Chem. 273 27205. PMID: 9765241. Gandiaet al (1996) Inhibition of nicotinic receptor-mediated responses in bovine chromaffin cells by diltiazem. Br.J.Pharmacol. 118 1301. PMID: 8818357. Ishibashiet al (1995) Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje neurons by diltiazem and verapamil. Brain Res. 695 88. PMID: 8574653. Daganiet al (1989) Effects of diltiazem on bioenergetics, K+ gradients, and free cytosolic Ca2+ levels in rat brain synaptosomes submitted to energy metabolism inhibition and depolarization. J.Neurochem. 53 1379. PMID: 2795006. Merck Index 123247. |