| 货号 | 3790/5 |
| 别名 | [D-Ala2,D-Leu5]-Enkephalin |
| 供应商 | Tocris |
| 生物活性 | Prototypicalδ-opioid receptor agonist that also displays activity at the μ-opioid receptor. Displays antinociceptive activity in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 569.66 |
| 分子式 | C29H39N5O7 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 63631-40-3 |
| 序列号 | YAGFL (Modifications: Ala-2 = D-Ala, Leu-5 = D-Leu) |
| 参考文献 | Keet al (2009) Delta opioid agonist [D-Ala2, D-Leu5] enkephalin (DADLE) reduced oxygen-glucose deprivation caused neuronal injury through the MAPK pathway. Brain Res. 1292 100. PMID: 19619518. Mulderet al (1991) Pharmacological profile of various κ-agonists at κ-, μ- and δ-opioid receptors mediating presynaptic inhibition of neurotransmitter release in the rat brain. Br.J.Pharmacol. 102 518. PMID: 1673074. Suh and Tseng (1990) Different types of opioid receptors mediating analgesia induced by morphine, DAMGO, DPDPE, DADLE and beta-endorphin in mice. Naunyn-Schmied.Arch.Pharmacol. 34267. |