| 货号 | 2294/10 |
| 别名 | 3'-Deoxyadenosine |
| 供应商 | Tocris |
| 生物活性 | Nucleoside analog that acts as an anticancer and antifungal agent. Can be converted to 3'-deoxyadenosine triphosphate (3'-dATP), which inhibits ATP-dependent DNA synthesis. Inhibits growth of various tumor cells in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 251.24 |
| 分子式 | C10H13N5O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 73-03-0 |
| 参考文献 | Kodamaet al (2000) Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells. Biochem.Pharmacol. 59 273. PMID: 10609556. Sugar and McCaffrey (1998) Antifungal activity of 3'-deoxyadenosine (cordycepin). Antimicrob.Agents Chemother. 42 1424. PMID: 9624488. Gumport and Edelheiet al (1976) The synthesis of 3'-dATP and its use as an inhibitor of ATP-dependent DNA synthesis in toluene-treated Escherichia coli. Biochemistry 15 2804. PMID: 779831. |