| 货号 | 2671/50 |
| 别名 | (11β,16α)-16,17-[Butylidenebis(oxy)]- |
| 供应商 | Tocris |
| 生物活性 | Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 430.53 |
| 分子式 | C25H34O6 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 51333-22-3 |
| 参考文献 | Wattenberget al (2007) Chemoprevention of pulmonary carcinogenesis by aerosolized budesonide in female A/J mice. Cancer Res. 575489. Pereiraet al (2006) Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors. Int.J.Cancer 1201150. Spenceret al (1995) Budesonide. A review of its pharmacological properties and therapeutic efficacy in inflammatory bowel disease. Drugs 50 854. PMID: 8586030. |