| 货号 | 4117/50 |
| 别名 | N-Benzyl-N-(3-isobutoxy-2-pyrrolidi |
| 供应商 | Tocris |
| 生物活性 | Calcium channel blocker. Also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels; opens mitochondrial KATP channels. Antiarrhythmic and antihypertensive; acts as a calcium sensitizer. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 403 |
| 分子式 | C24H34N2O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Satoet al (2006) Bepridil, an antiarrythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. J.Pharmacol.Exp.Ther. 316 182. PMID: 16174795. Wantanabe and Kimura (2001) Blocking effect of bepridil on Na+/ Ca2+ exchange current in gunea pig cardiac ventricular myocytes. Jpn.J.Pharmacol. 85 370. PMID: 11388640. Gillet al (1992) Pharmacology of bepridil. Am.J.Cardiol. 69 11D. PMID: 1372785. Yataniet al (1986) Bepridil block of cardiac calcium and sodium channels. J.Pharmacol.Exp.Ther. 237 9. PMID: 2420970. |