货号 | 5584/50 |
别名 | 7-[4-[4-(2,3-Dichlorophenyl)-1-pipe |
供应商 | Tocris |
生物活性 | High affinity dopamine D2 and 5-HT1A receptor partial agonist (Ki values are ~1.64 and 5.59 nM respectively). Also 5-HT2A antagonist (Ki = 8.7 nM). Suppresses morphine-induced emesis in vivo. Atypical antipsychotic. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >99 % |
计算分子量 | 448.39 |
分子式 | C23H27Cl2N3< |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Shiokawaet al (2007) Usefulness of the dopamine system-stabilizer aripiprazole for reducing morphine-induced emesis. Eur.J.Pharmacol. 570 108. PMID: 17678644. Davieset al (2004) Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology. CNS Drug Rev. 10 317. PMID: 15592581. |