| 货号 | 1706/100 |
| 别名 | N-(4-Hydroxyphenyl)acetamide; Paracetamol |
| 供应商 | Tocris |
| 生物活性 | Cyclooxygenase inhibitor; may be selective for COX-3 (IC50 values are 460, > 1000 and > 1000 μM for canine COX-3, and murine COX-1 and COX-2 respectively). Widely used analgesic and antipyretic agent. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 151.16 |
| 分子式 | C8H9NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 103-90-2 |
| 参考文献 | Chandrasekharanet al (2002) COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc.Natl.Acad.Sci.U.S.A. 99 13926. PMID: 12242329. Chonget al (2001) Effect of acetaminophen on atherosclerosis. Ann.Pharmacother. 35 1476. PMID: 11724102. Riendeauet al (1997) Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDS) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. Can.J.Physiol.Pharmacol. 75 1088. PMID: 9365818. |