| 货号 | 3618/50 |
| 别名 | 3-(Acetylamino)-1-propanesulfonic acid hemicalcium salt; Calcium acetylhomotaurinate |
| 供应商 | Tocris |
| 生物活性 | GABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 200.24 |
| 分子式 | C10H20CaN2O8S2 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 77337-73-6 |
| 参考文献 | Popp and Lovinger (2000) Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur.J.Pharmacol. 394 221. PMID: 10771287. Bertonet al (1998) Acamprosate enhances N-methyl-D-aspartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons. Alcohol Clin.Exp.Res. 22 183. PMID: 9514305. Spanagelet al (1996) Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur.J.Pharmacol. 305 39. PMID: 8813529. |