| 货号 | 9944P |
| 供应商 | CST |
| 背景 | AICAR (5-Aminoimidazole-4-carboxyamide ribonucleoside) is an adenosine analog taken up by muscle and phosphorylated to form 5-aminoimidazole-4-carboxamide-1--D-ribofuranosyl-5-monophosphate (ZMP), which stimulates AMPK activity and glucose transport in skeletal muscle (1). AICAR has been used in studies measuring glucose uptake, diabetes and insulin resistance, and energy regulation during exercise. AICAR acts by entering nucleoside pools and significantly increasing levels of adenosine during periods of ATP breakdown (2). |
| 运输条件 | 0.75 |
| 存放说明 | -20C |
| 参考文献 | Sakoda, H. et al. (2002) Am. J. Physiol. Endocrinol. Metab. 282, E1239-E1244. Mullane, K. et al. (1993) Trends Cardiovasc. Med. 3, 227-234. Jakobsen, S. N. et al. (2001) J. Biol. Chem. 276, 46912-46916. Jessen, N. et al. (2003) J. Appl. Physiol. 94, 1373-1379. Giri, S. et al. (2004) J. Neurosci. 24, 479-487. |
