GSK-J4 (Free base)
货号：
2762-1 基本售价：
1220.5 元 规格：
1mg
产品信息
概述| 货号 | 2762-1 |
| 描述 | GSK- J4 is cell-permeable ethyl ester of GSK-J1 (Cat. Nos. 2260 & 2761). Acts as a histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC₅₀ = 9 μM for the inhibition of TNFα release). Rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| CAS号 | 1373423-53-0 |
| 外观 | Yellow waxy solid |
