Ethidium Bromide
货号:
1203-10 基本售价:
1220.5 元 规格:
10ml
产品信息
概述货号 | 1203-10 |
反应种属 | Human, Mouse, Rat |
应用 | WB, IH |
性能供应商 | Biovision |
Entrez Gene IDs | 7294 |
纯化方式 | Affinity purified |
背景 | Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Like ITK, can phosphorylate PLCG1, leading to its localization in lipid rafts and activation, followed by subsequent cleavage of its substrates. |
运输条件 | Blue Ice |
存放说明 | +4℃ |
CAS号 | 1239-45-8 |
外观 | Colorless liquid |