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货号： bs-2601R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-2601R
- 英文名称
- IL5RA
- 中文名称
- 白介素-5受体α链抗体IL-5Rα
- 别 名
- Interleukin-5 receptor alpha; CD125 antigen; CDw125; HSIL5R3; IL5R; IL-5R; Interleukin 5 Receptor alpha; Interleukin 5 receptor subunit alpha; interleukin 5 receptor type 3; MGC26560; IL5RA; IL-5R alpha; IL5RA_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 转录调节因子 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 46kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL-5R alpha:11-110/420 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Function:
This is the receptor for interleukin-5. The alpha chain binds to IL5.
Subunit:
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with SDCBP.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed on eosinophils and basophils.
Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.
SWISS:
Q01344
Gene ID:
3568
Database links:Entrez Gene: 3568 Human
Entrez Gene: 16192 Mouse
Omim: 147851 Human
SwissProt: Q01344 Human
SwissProt: P21183 Mouse
Unigene: 207105 Human
Unigene: 68876 Human
Unigene: 3448 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
testis (mouse) Lysate at 40 ug
lung (mouse) Lysate at 40 ug
ovary (mouse) Lysate at 40 ug
A549 (human)cell Lysate at 40 ug
Primary: Anti- IL5RA(bs-2061R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46kD
Observed band size: 56 kD