Calmidazolium (chloride)
货号：
14442-10mg 基本售价：
1190.0 元 规格：
10 mg
产品信息
概述| 货号 | 14442-10mg |
| 描述 | Calmidazolium (chloride) is an inhibitor of calmodulin (CaM), inhibiting CaM-dependent phosphodiesterase and CaM-induced activation of erythrocyte calcium-transporting ATPase (IC50 = 0.15 and 0.35 µM, respectively).1 Calmidazolium also inhibits an array of calcium-transporting ATPases, including those from heart and skeletal muscle (IC50 = 2.1 and 2.9 µM, respectively).1 It also induces the influx of extracellular calcium through store-operated calcium channels (EC50 = 3 µM).2,3 |
| 别名 | R 24571; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gietzen, K. Comparison of the calmodulin antagonists compound 48/80 and calmidazolium. Biochemistry Journal 216(3), 611-616 (1983).
2.Harper, J.L. and Daly, J.W. Effect of calmidazolium analogs on calcium influx in HL-60 cells. Biochemical Pharmacology 60(3), 317-324 (2000).
3.Peppiatt, C.M.,Holmes, A.M.,Seo, J.T., et al. Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells. Biochemistry Journal 381(3), 929-939 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥98% |
| 计算分子量 | 687.7 |
| 分子式 | C31H23Cl6N2O • Cl |
| CAS号 | 57265-65-3 |
| 稳定性 | ≥ 6 months |
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