| 货号 | 4089/50 |
| 别名 | 3'-[α-Amino-p-methoxyhydrocinnamamido |
| 供应商 | Tocris |
| 生物活性 | Protein synthesis inhibitor; leads to the premature release of polypeptide chains as polypeptidyl purine derivatives. Analog of the 3' end of aminoacyl-tRNA. Aminonucleoside antibiotic. Inhibits translation in both in vitroandin vivo systems. Also inhibits the transport of proteins into the mitochondria in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 544.43 |
| 分子式 | C22H29N7O5.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 58-58-2 |
| 参考文献 | Price and Verner (1993) Puromycin inhibits protein import into mitochondria by interfering with an intramitochondrial ATP-dependent reaction. Biochim.Biophys.Acta. 1150 89. PMID: 8334141. Azzam and Algranati (1973) Mechanism of puromycin action: fate of ribosomes after release of nascent polypeptide chains from polysomes. Proc.Nat.Acad.Sci. 703866. |