| 货号 | 3256/50 |
| 别名 | 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1 |
| 供应商 | Tocris |
| 生物活性 | Selectiveβ1-adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1,β2andβ3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 342.4 |
| 分子式 | C15H25NO3.紺4H6O6 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 56392-17-7 |
| 参考文献 | Dasbiswaset al (2008) S-metoprolol: The 2008 Clinical Review. J.Indian.Med.Assoc. 106 259. PMID: 18828349. Hoffmannet al (2004) Comparative pharmacology of human β-adrenergic receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmied.Arch.Pharmacol. 369151. Garlichset al (1999) Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells. Eur.J.Clin.Invest. 29 12. PMID: 10092983. |