货号 | 3090/50 |
别名 | 3',4',5',6'-Tetrahydroxyspiro[isobenzof |
供应商 | Tocris |
生物活性 | Inhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >97 % |
计算分子量 | 364.31 |
分子式 | C20H12O7 |
可溶性/溶解性 | Soluble to 75 mM in DMSO and to 10 mM in ethanol |
CAS号 | 2103-64-2 |
参考文献 | Ukhanovet al (2011) Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons. J.Neurosci. 31 273. PMID: 21209212. Lehmannet al (2008) Small molecule disruption of G protein βγ subunit signaling inhibits neutrophil chemotaxis and inflammation. Mol.Pharmacol. 73 410. PMID: 18006643. |